Product Details
Catalog No./Size: GMH0041F-025/25 TestsGMH0041F-100/100 Tests
Vol.per.Test: 10 μl/Test
Clone: EDU-2
Isotype: Mouse IgG2a
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Storage Condition: Store at 4�C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Applications: Flow Cytometry
Applications Notes:

FACS: Use 10µl for 106 cells
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Description:

CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages. CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.