CatalogNo./Size: | GMH0291F-025/25Tests GMH0291F-100/100Tests | |
Vol.per.Test: | 10μl/Test | |
Clone: | GMCD29 | |
Isotype: | MouseIgG1 | |
Reactivity: | Human,Notyettestedinotherspecies. | |
Workshop: | N/A | |
StorageBuffer: | Phosphate-bufferedsolution,pH7.4,containing0.09%sodiumazideand0.2%(w/v)BSA | |
StorageCondition: | Storeat4�C.DONOTFREEZE.LIGHTSENSITIVEMATERIAL. | |
Applications: | FlowCytometry | |
ApplicationsNotes: | FACS:Use10µlfor106cells | |
Description: | GMCD29reactswith130kDaintegrinb1,whichhasabroadtissuedistribution.Itisexpressedonlympnocytes,monocytesandweaklyongranulovytes,butnotonerythrocytes.OnTcells,CD29ismorehighlyexpressedonmemorycellsthannaivecells.Integrinchainbasociatedwithintegrinasubunits1-6(CD49a-f)toformCD49/CD29heterodimersthatareinvolvedincell-cellandcell-matrixadhesion.IthasbeenreportedthatCD29isacriticalmoleculeforembryogenesisanddevelopment.Italsoessentialtothedifferentiationofhematopoieticstemcellsandassociatedwithtumorprogressionandmetastasis.Thiscloneiscrossreactivewithnon-humanprimate. |