| CatalogNo./Size: | GMH0142P-025/25Tests GMH0142P-100/100Tests | |
| Vol.per.Test: | 10μl/Test | |
| Clone: | GM2CD14 | |
| Isotype: | MouseIgG1 | |
| Reactivity: | Human,Notyettestedinotherspecies. | |
| Workshop: | N/A | |
| StorageBuffer: | Phosphate-bufferedsolution,pH7.4,containing0.09%sodiumazideand0.2%(w/v)BSA | |
| StorageCondition: | Storeat4�C.DONOTFREEZE.LIGHTSENSITIVEMATERIAL. | |
| Applications: | FlowCytometry | |
| ApplicationsNotes: | FACS:Use10µlfor106cells | |
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| Description: | GM2CD14reactswithCD14,a53-55kDamolecule.CD14isahumanhighaffinitycell-surfacereceptorforcomplexesoflipopolysaccharide(LPS-endotoxin)andserumLPS-bindingprotein(LPB).CD14antigenhasastrongpresenceonthesurfaceofmonocytes/macrophages,isweaklyexpressedongranulocytes,butnotexpressedbymyeloidProgenitorcells.CD14functionsasareceptorforendotoxin;whenthemonocytesbecomeactivatedtheyreleasecytokinessuchasTNF,andup-regulatecellsurfacemoleculesincludingadhesionmolecules.Thiscloneiscrossreactivewithnon-humanprimate. | |