CatalogNo./Size: | GMH0222F-025/25Tests GMH0222F-100/100Tests | |
Vol.per.Test: | 10μl/Test | |
Clone: | GM1CD22 | |
Isotype: | MouseIgG1 | |
Reactivity: | Human,Notyettestedinotherspecies. | |
Workshop: | N/A | |
StorageBuffer: | Phosphate-bufferedsolution,pH7.4,containing0.09%sodiumazideand0.2%(w/v)BSA | |
StorageCondition: | Storeat4�C.DONOTFREEZE.LIGHTSENSITIVEMATERIAL. | |
Applications: | FlowCytometry | |
ApplicationsNotes: | FACS:Use10µlfor106cells | |
Description: | GM1CD22reactswithCD22,a140kDaB-cellspecificmolecule,expressedinthecytoplasmofallBlymphocytesandonthecellsurfaceofonlymatureBcells.CD22antigenispresentinthemostB-cellleukemiasandlymphomasbutnotT-cellleukemias.IncontrastwithCD10,CD19andCD20antigen,CD22antigenisstillpresentonlymphoplasmacytoidcellsbutisdininishedonthefullymatureplasmacells.CD22isanadhesionmoleculeandplaysaroleinBcellactivationasasignalingmolecule. |